Narrative review uncovers mechanisms of CD40L in atherothrombotic disease, highlighting its contribution to platelet activation and arterial plaque rupture.
Recent data suggests that CD40L is involved in the pathogenesis of atherothrombotic disease. This review will focus on the history of CD40L, its role in platelet-mediated pathogenesis of atherothrombotic disease, its association to clinical syndromes and procedures, and its role in determining plaque rupture.
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Anand et al. (2003) studied this question.
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