Report proposes a new framework for real-time monitoring of biological systems, implying advances in precision medicine.
This report proposes a disruptive framework rooted in “Status-Relational Entropy (SRE) Dynamics”, redefining physical reality as a macroscopic emergence of informational statistics to bypass traditional biochemical "black-box" experimentation. We hypothesize that biological entities—such as cells and neural networks—are fundamentally high-order algorithmic modules or "causal clusters" operating within a discrete causal network. By modeling the ontology of light as an open-ended Möbius topological ribbon rather than a substance traversing spatial bounds, this framework establishes a deterministic, single-channel, full-duplex communication channel that guarantees instantaneous and isotropic mutual information updates. To achieve lossless signal separation without propagation delays, we implement a **Bidirectional Topological Flow Density Subtractor** algorithm at the receiving boundary. By sampling response vectors via adjacent observation channels, we construct a 2 × 2 complex Hermitian Cross-Spectral Matrix $M(f)$ and analytically extract its eigenvalue spacing Δλ through a first-order closed-form solution. The forward causal flow density (ρA→ B), being a locally known variable, is algebraically subtracted from the global observed density (ρₜₒₜₐₗ = α · Δλ) to instantaneously isolate the reverse target signal (ρB→ A). Furthermore, we integrate “Random Matrix Theory (RMT)” heuristic sieves utilizing the Wigner Surmise for the Gaussian Unitary Ensemble (GUE) to isolate coherent causal flows from environmental multi-path scattering and chaotic topological noise. Leveraging the Principle of Functional Interchangeability, we introduce an innovative **Inverse AI Model Weight Inference** research paradigm. By capturing spectral invariants—such as eigenvalue spacing and condition numbers—researchers can utilize micro-frequency drifts (Δλ fluctuations) to back-propagate physical observables directly onto digital model weights or connectivity matrices, enabling non-invasive, real-time cellular health monitoring. This methodology facilitates "random access" to underlying biological causal chains, potentially reducing the time and cost of fundamental research by orders of magnitude. While constrained by a "Read-Only" universe-level encryption firewall that limits intervention to rendered outputs, this framework transitions life sciences from an empirical era to a deductive, algebraic paradigm, driving a new epoch of precision medicine governed by causal dynamics.
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Yue Lu (2026) studied this question.
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