Population
Mathematical model of the ventricle based on Luo-Rudy cellular formulation modified for studying ischemic…
Design
Preclinical
Authors
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Mathematical modeling suggests that the proarrhythmic potential of Class I antiarrhythmic drugs in ischemia is driven by both unbinding rates and binding affinity, which create nonuniform dispersion of refractoriness.
Mathematical modeling suggests that the proarrhythmic potential of Class I antiarrhythmic drugs in ischemia is driven by both unbinding rates and binding affinity, which create nonuniform dispersion of refractoriness.
Cimponeriu et al. (2003) studied this question.
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