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We report a case of spontaneous restoration of corneal clarity after graft displacement following Descemet membrane endothelial keratoplasty. The patient had a functioning glaucoma filtering bleb into which air from the anterior chamber escaped, resulting in poor adherence of the graft. The graft was displaced temporally from the optical axis. Corneal edema cleared spontaneously within 6 weeks, and the central cornea remained clear throughout the 11-month follow-up, suggesting that endothelial cells migrated from the eccentric donor graft to the recipient cornea. This might justify the use of smaller donor grafts, and thus a single donor graft might be sufficient for multiple patients. Financial Disclosure None of the authors has a financial or proprietary interest in any material or method mentioned.
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John et al. (2016) studied this question.
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