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November 1, 1987AnesthesiologyOpen Access

Pulsed Doppler Ascending Aortic, Carotid, Brachial, and Femoral Artery Blood Flows during Caudal Anesthesia in Infants

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Why the study?

Does caudal bupivacaine anesthesia alter systemic and regional hemodynamics in anesthetized infants?

Population

8 infants, mean age 6.5 +/- 0.5 months, weighing 7.4 +/- 4.4 kg, anesthetized with halothane 0.2% end-tidal…

Comparison

Caudal bupivacaine anesthesia vs Baseline (prior to caudal anesthesia)

Design

Cohort

Authors

DPDidier PayenUniversité Claude Bernard Lyon 1CEClaude EcoffeyUniversité Paris-SudPCPierre CarliUniversité Paris Cité

Discussion

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Implication

May support avoiding volume loading in normovolemic infants; hypothesis-generating for hemodynamic management during caudal anesthesia.

Structured PICO

Does caudal bupivacaine anesthesia alter systemic and regional hemodynamics in anesthetized infants?

P
Population
8 infants, mean age 6.5 +/- 0.5 months, weighing 7.4 +/- 4.4 kg, anesthetized with halothane 0.2% end-tidal and 60% nitrous oxide.
I
Intervention
Caudal bupivacaine anesthesia
C
Comparator
Baseline (prior to caudal anesthesia)
O
Outcome
Hemodynamic effects including heart rate, arterial pressure, cardiac index, stroke index, and regional blood flows and vascular resistances assessed by pulsed Dopplersurrogate

Caudal anesthesia in infants induces reflex vasoconstriction in innervated areas to maintain cardiac output, suggesting volume loading is unnecessary in normovolemic infants.

Cite This Study

Payen et al. (1987) studied this question.

synapsesocial.com/papers/6a71a04be36a167817e363dfhttps://doi.org/10.1097/00000542-198711000-00011
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Hemodynamic Effects of Pediatric Caudal Anesthesia Assessed by Esophageal Doppler2002 · 40 citations
  2. 2The hemodynamic effects of newborn caudal anesthesia assessed by transthoracic echocardiography: a randomized, double‐blind, controlled study2008 · 15 citations
  3. 3Pulmonary Doppler flow velocity pattern during caudal epidural anaesthesia in children2002 · 6 citations
  4. 4Effect of different volumes of bupivacaine 0.25% caudal blocks on cardiac index measured by electrical cardiometry in children undergoing elective lower abdominal surgeries: A randomised controlled trial2025 · 1 citations
  5. 5Effects of awake caudal anesthesia on mean arterial blood pressure in very low birthweight infants2020 · 4 citations