Why the study?
Does Org 10172 prevent deep-vein thrombosis as effectively as low-dose heparin in patients with acute ischaemic stroke?
Population
179 patients with acute ischaemic stroke resulting in limb paresis
Comparison
Org 10172 1250 anti-Xa Units s.c. once daily… vs Heparin sodium 5000 IU s.c. twice daily
Design
RCT, randomized, double-blind
Follow-up
2-3 months
Authors
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Supports Org 10172 as effective alternative to heparin for DVT prophylaxis in acute ischaemic stroke; confirms comparable rates in this RCT.
Does Org 10172 prevent deep-vein thrombosis as effectively as low-dose heparin in patients with acute ischaemic stroke?
Once-daily Org 10172 is as effective and safe as twice-daily low-dose heparin for DVT prophylaxis in patients with acute ischaemic stroke.
Dumas et al. (1994) studied this question.
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