What question did this study set out to answer?

To evaluate the impact of a pilsicainide challenge on right ventricular longitudinal myocardial strain in patients with Brugada-type electrocardiograms using two-dimensional strain imaging.

December 1, 2006European Journal of EchocardiographyOpen Access

192 Longitudinal myocardial strain in right ventricular wall reduced by pilsicainide challenge in patients with Brugada type electrocardiography. Evaluation by two dimensional strain imaging technique

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Why the study?

Does pilsicainide challenge reduce longitudinal myocardial strain in the right ventricular wall in patients with Brugada type electrocardiography?

Key Points

To evaluate the impact of a pilsicainide challenge on right ventricular longitudinal myocardial strain in patients with Brugada-type electrocardiograms using two-dimensional strain imaging.
Administered a pilsicainide drug challenge to provoke or unmask Brugada-type electrocardiographic patterns in patient subjects.
Quantified regional right ventricular wall myocardial deformation using two-dimensional strain echocardiographic imaging.
Pilsicainide challenge induced a notable reduction in longitudinal myocardial strain within the right ventricular wall.
Two-dimensional strain imaging revealed localized right ventricular mechanical dysfunction accompanying the electrical abnormalities of Brugada-type patterns.

Structured PICO

Does pilsicainide challenge reduce longitudinal myocardial strain in the right ventricular wall in patients with Brugada type electrocardiography?

Population

Patients with Brugada type electrocardiography

Intervention

Pilsicainide challenge

Outcome

Longitudinal myocardial strain in right ventricular wall evaluated by two-dimensional strain imaging techniquesurrogate

Discussion

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Implication

Pilsicainide challenge reduces longitudinal myocardial strain in the right ventricular wall in patients with Brugada type ECG.

Cite This Study

Murata et al. (2006) studied this question.

synapsesocial.com/papers/6a71a9496c240de38cdc31f2 https://doi.org/10.1016/s1525-2167(06)60042-5

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192 Longitudinal myocardial strain in right ventricular wall reduced by pilsicainide challenge in patients with Brugada type electrocardiography. Evaluation by two dimensional strain imaging technique

Key Points

Structured PICO

Discussion

Implication

Cite This Study

192 Longitudinal myocardial strain in right ventricular wall reduced by pilsicainide challenge in patients with Brugada type electrocardiography. Evaluation by two dimensional strain imaging technique

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider