Population
A 4-month-old girl, her brother, and their father harboring an SCN5A mutation.
Design
Case_series
Authors
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May prompt SCN5A evaluation in febrile infants with arrhythmias; leaves open evidence-based preventive strategies.
SCN5A loss-of-function mutations can present in early infancy with fever-induced life-threatening arrhythmias, highlighting the need for aggressive antipyretic and beta-blocker therapy during febrile episodes.
Chockalingam et al. (2010) studied this question.
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