Key result
The single-syringe technique of adenosine administration was non-inferior to the double-syringe technique for terminating stable supraventricular tachycardia, achieving a 100% termination rate versus 93.3% (p=1.000).
Why the study?
Guidelines recommend the double-syringe technique for adenosine administration in stable SVT, but a newly proposed single-syringe technique may be beneficial and was hypothesized to be noninferior.
Does the single-syringe technique of adenosine administration improve or maintain SVT termination rates in patients with stable supraventricular tachycardia compared to the standard double-syringe technique?
Comparison
Single-syringe technique vs double-syringe technique of adenosine administration
Design
Pilot multicenter single-blind randomized controlled noninferiority study
Authors
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May simplify adenosine administration for SVT termination; leaves open need for larger confirmatory trials.
RCT (n=30)
Single-blind
Computerized block randomization
Yes
Does the single-syringe technique of adenosine administration improve or maintain SVT termination rates in patients with stable supraventricular tachycardia compared to the standard double-syringe technique?
Absolute Event Rate: 100% vs 93.3%
p-value: p=1.000
The single-syringe technique for adenosine administration is a practical, safe, and non-inferior alternative to the conventional double-syringe technique for terminating stable supraventricular tachycardia.
Kotruchin et al. (2022) conducted an RCT in Supraventricular tachycardia (SVT) (n=30). Single-syringe technique (SST) of adenosine administration vs. Double-syringe technique (DST) of adenosine administration was evaluated on Success rate of SVT termination (p=1.000). The single-syringe technique of adenosine administration was non-inferior to the double-syringe technique for terminating stable supraventricular tachycardia, achieving a 100% termination rate versus 93.3% (p=1.000).
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