Adenosine versus intravenous calcium channel antagonists for supraventricular tachycardia
Why the study?
Does adenosine improve the rate of reversion to sinus rhythm compared to intravenous calcium channel antagonists in patients with supraventricular tachycardia?
Population
Patients of any age presenting with supraventricular tachycardia (SVT)
Comparison
Adenosine vs Intravenous calcium channel antagonists (CCAs)
Design
Meta-analysis
Authors
Discussion
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Member takes
Implication
Similar SVT termination rates and adverse events with adenosine or CCAs; confirms equivalence and supports individualized first-line selection.
Structured PICO
Does adenosine improve the rate of reversion to sinus rhythm compared to intravenous calcium channel antagonists in patients with supraventricular tachycardia?
P
Population
Patients of any age presenting with supraventricular tachycardia (SVT)
I
Intervention
Adenosine
C
Comparator
Intravenous calcium channel antagonists (CCAs)
O
Outcome
Rate of reversion to sinus rhythm and major adverse effects
Adenosine and intravenous calcium channel antagonists appear similarly effective for reverting supraventricular tachycardia to sinus rhythm, with no appreciable difference in the incidence of hypotension.
Limitations
- Included trials did not report length of stay in hospital nor patient satisfaction
- Lack of studies comparing patient experiences and prospectively studied adverse events
Cite This Study
Alabed et al. (2017) studied this question.