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July 4, 2012Circulation Cardiovascular Interventions

Flow Patterns at Stented Coronary Bifurcations

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Key result

In computer simulations, single main branch stenting offered hemodynamic advantages over double stenting, while crush stenting provided the most favorable results among double-stenting techniques.

Why the study?

Do different coronary bifurcation stenting techniques result in different hemodynamic profiles in computational models?

Population

Computer simulation models of coronary bifurcations

Comparison

Various single- and double-stenting techniques vs Comparison among the different stenting techniques

Design

Other

Authors

DKDemosthenes G. KatritsisElectrophysiologyATA. TheodorakakosPanos Institute West AfricaIPIoannis PantosUniversity of Ioannina

Discussion

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Implication

Simulation data favor single over double bifurcation stenting; extends modeling but leaves clinical translation open.

Structured PICO

Do different coronary bifurcation stenting techniques result in different hemodynamic profiles in computational models?

P
Population
Computational fluid dynamics analysis of coronary bifurcation models to assess hemodynamic parameters after various single- and double-stenting techniques.
I
Intervention
Various single- and double-stenting techniques (single main branch stenting with or without side branch balloon angioplasty, crush stenting, T-stenting, culotte technique)
C
Comparator
Comparison among the different stenting techniques
O
Outcome
Distributions and surface integrals of time averaged wall shear stress (TAWSS), oscillatory shear index (OSI), and relative residence time (t(r))surrogate

Computational fluid dynamics suggest that single main branch stenting provides better hemodynamic profiles than double stenting at coronary bifurcations.

Cite This Study

Katritsis et al. (2012) studied Coronary bifurcations. Single main branch stenting vs. Double-stenting techniques (crush, T-stenting, culotte) was evaluated on Hemodynamic parameters (time averaged wall shear stress, oscillatory shear index, and relative residence time). In computer simulations, single main branch stenting offered hemodynamic advantages over double stenting, while crush stenting provided the most favorable results among double-stenting techniques.

synapsesocial.com/papers/6a71ae48e36a167817e36bb2https://doi.org/10.1161/circinterventions.112.968347

Topics

Coronary artery diseaseCoronary CT angiography
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Percutaneous coronary intervention for bifurcation coronary disease2004 · 212 citations
  2. 2Double Versus Single Stenting for Coronary Bifurcation Lesions2009 · 126 citations
  3. 3Effect of Endothelial Shear Stress on the Progression of Coronary Artery Disease, Vascular Remodeling, and In-Stent Restenosis in Humans2003 · 434 citations
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