Key result
A blood pressure profile performed over one hour yielded clinically equivalent results to a three-hour profile, achieving BHS grade B and A validation for SBP and DBP respectively.
Why the study?
Does a 1-hour blood pressure profile yield clinically equivalent results to a 3-hour profile in pregnant women?
Observational (n=80)
Does a 1-hour blood pressure profile yield clinically equivalent results to a 3-hour profile in pregnant women?
A 1-hour blood pressure profile yields clinically equivalent results to a 3-hour profile in pregnant women, with added psychosocial and financial benefits.
One-hour BP profiles may suffice for validation in pregnancy cohorts; leaves open whether shorter protocols improve clinical outcomes or warrant practice change.
BACKGROUND: A blood pressure profile (BPP) is often used to diagnose and manage hypertension in pregnancy. However, there is no consensus on the number and interval of blood pressure (BP) readings required. AIMS: To ascertain whether BP readings at 15-min interval over one hour yields clinically equivalent results to readings at 60-min interval over three hours. MATERIALS AND METHODS: Eighty unique women were recruited to this prospective study. Automated BP machines were used to take readings at 15-min interval over one hour and at 60-min interval over three hours. The mean systolic and diastolic BPs obtained using each regimen were calculated and compared. Women also completed a questionnaire to evaluate the psychosocial and financial impact of a prolonged outpatient investigation. RESULTS: BP readings from 67 patients were included for analysis. Clinical equivalence was assessed using the British Hypertension Society (BHS) validation criteria for comparing nonmercury devices to the gold-standard calibrated mercury device. Mean SBP readings for 54% (36/67), 90% (60/67) and 97% (65/67) and mean DBP readings for 73% (49/67), 94% (63/67) and 100% (67/67) were within 5, 10 and 15 mmHg agreement across the two time regimens which achieved grade B and grade A validation, respectively. A BPP was costly and stressful for women and affected their ability to attend work and look after other children. CONCLUSIONS: A BPP performed over one hour compared to over three hours yields clinically equivalent results, yet has psychosocial and financial advantages.
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Chohan et al. (2016) conducted an observational in Hypertension in pregnancy (n=80). Blood pressure readings at 15-min intervals over one hour vs. Blood pressure readings at 60-min intervals over three hours was evaluated on Clinical equivalence of mean systolic and diastolic BPs using British Hypertension Society (BHS) validation criteria. A blood pressure profile performed over one hour yielded clinically equivalent results to a three-hour profile, achieving BHS grade B and A validation for SBP and DBP respectively.
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