Key result
Transcatheter closure of ventricular septal defects using a vascular single disc PDA device was successful in 99.3% of cases (135/136), with no residual shunt observed at 1-year follow-up.
Why the study?
Does transcatheter closure with a vascular single disc PDA device safely and effectively treat selected cases of perimembranous and muscular VSD?
Observational (n=136)
Does transcatheter closure with a vascular single disc PDA device safely and effectively treat selected cases of perimembranous and muscular VSD?
Transcatheter closure of perimembranous and muscular VSDs using a vascular single disc PDA device appears safe and effective, with high procedural success and no residual shunts at 1 year.
May offer an alternative device for VSD closure; leaves open need for randomized comparisons to approved devices.
perimembranous in 125 cases, muscular in 08 cases and apical in 03 cases.The procedure was performed in 136 cases with Vascular PDA device (Cocoon).Procedure: LV Angiography was done to locate the morphology & position VSD.Lima/JR Catheter was passed in LV & anchored in VSD with rotation and pull back technique.It was crossed with Double length Terumo 0.035" x 260 cm wire and it was placed in RV->RA->IVC/SVC/PA.It was snared through femoral vein and arteriovenous Loop was created with the help of Terumo wire.Long device sheath was passed on it through RA, RV and then into Aorta using Kissing technique.Sheath was positioned in LV.PDA device was loaded in sheath.Device was positioned on LV side first and then on RV side.Aortogram to look for any AR and LV angiogram to check the optimum positioning was taken along with 2D-Echo which if found to be accurate, device was delivered.Post procedure treatment with steroids was advised as per standard treatment.Results: Procedure was done successfully in 135 without any complications.In those 29 cases Transient BBB was developed on during the procedure.In 1 case complication of CHB occurred during the procedure in which temporary pace maker (TPM) was implanted for 3 days.In another case, complication of CHB occurred in ICU after 3 hours in which TPM was done for 2 days.In 2 cases device embolizied, 1 device successfully retrieved with help of the basket snare and procedure was completed with bigger size device, another 1 case was sent for surgery. 1 case of death was observed on 5th day, which was due to stroke.At 1 year follow up no shunt was noted in ECHO Cardiograph and ECG didn't show any delayed BBB.Conclusion: Transcatheter closure with vascular single disc PDA device is safe and efficacious in selected cases of perimembranous and muscular VSD using PDA device.
No takes yet. Share an insight, caveat, or question.
Swamy et al. (2018) conducted an observational in Ventricular septal defect (VSD) (n=136). Transcatheter closure with Vascular PDA device (Cocoon) was evaluated on Procedural success. Transcatheter closure of ventricular septal defects using a vascular single disc PDA device was successful in 99.3% of cases (135/136), with no residual shunt observed at 1-year follow-up.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: