Key result
The modified Valsalva manoeuvre significantly increased the rate of sinus rhythm restoration at 1 minute compared to the standard Valsalva manoeuvre (43% vs 17%, OR 3.7).
Why the study?
Guidelines recommend vagal manoeuvres as first-line therapy for stable SVT but lack clear recommendations regarding which manoeuvre to use, particularly in resource-limited primary care settings.
Does the modified Valsalva manoeuvre improve the restoration of sinus rhythm in patients with stable narrow complex tachyarrhythmias in primary care?
Does the modified Valsalva manoeuvre improve the restoration of sinus rhythm in patients with stable narrow complex tachyarrhythmias in primary care?
Odds Ratio: 3.7 (95% CI 2.3–5.8)
Absolute Event Rate: 43% vs 17%
p-value: p=< 0.0001
The modified Valsalva manoeuvre is a safe, effective, and pragmatic first-line intervention for stable SVT in primary care, especially where adenosine is unavailable.
May support modified Valsalva for SVT termination; leaves open prospective validation before practice change.
Supraventricular tachydysrhythmias (SVTs) are a common presenting complaint, with a national prevalence of 3/1000 persons. While most commonly stable, prolonged paroxysms can deteriorate into haemodynamically unstable subtypes or ventricular dysrhythmias. Early recognition with appropriate management is critical to reducing the morbidity associated with this condition. The American Heart Association holds that vagal manoeuvres are a first-line therapy in the management algorithm of stable SVTs. However, they state that no clear recommendations can be made around which manoeuvre to use, highlighting that future research should examine the efficacy and safety profiles of the various manoeuvres. In the South African primary care setting, clinicians must be at the forefront of pragmatic management strategies in the face of resource limitations, such as the unavailability of adenosine - a second-line therapy when vagal manoeuvres fail. In this article, we begin with a case study and review the literature around vagal manoeuvres.
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Murphy et al. (2022) conducted a review in Supraventricular tachycardia (n=428). Modified Valsalva manoeuvre vs. Standard Valsalva manoeuvre was evaluated on Presence of sinus rhythm at 1 min (OR 3.7, 95% CI 2.3-5.8, p=< 0.0001). The modified Valsalva manoeuvre significantly increased the rate of sinus rhythm restoration at 1 minute compared to the standard Valsalva manoeuvre (43% vs 17%, OR 3.7).
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