Why the study?
What are the hemodynamic and metabolic effects of removing 15 to 20% of blood volume in normal subjects?
Population
11 normal subjects
Comparison
Removal of 15 to 20% of blood volume within 35… vs Baseline (before blood removal)
Design
Other
Follow-up
Immediate (after 35 minutes)
Authors
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Tolerates moderate blood loss without overt changes in normals; leaves open compensatory limits in disease or shock.
What are the hemodynamic and metabolic effects of removing 15 to 20% of blood volume in normal subjects?
The splanchnic circulation functions as an important blood reservoir in humans, allowing tolerance of 15-20% blood loss without conspicuous hemodynamic changes.
Price et al. (1966) studied this question.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: