Key result
This review summarizes literature on the perioperative handling of antiplatelet drugs and analyzes the pharmacokinetic and pharmacodynamic characteristics of newer agents.
Why the study?
Does the continuation of antiplatelet drugs compared to withdrawal affect the balance of bleeding and thrombotic risk in patients with coronary stents undergoing non-cardiac surgery?
Does the continuation of antiplatelet drugs compared to withdrawal affect the balance of bleeding and thrombotic risk in patients with coronary stents undergoing non-cardiac surgery?
This review emphasizes that in patients with coronary stents undergoing non-cardiac surgery, the risk of coronary thrombosis from withdrawing antiplatelets often outweighs the risk of surgical bleeding from continuing them.
Supports continuing antiplatelets in stented patients undergoing noncardiac surgery; leaves open need for randomized trials to confirm risk balance.
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Minno et al. (2013) conducted a review in Patients on antiplatelet therapy undergoing non-cardiac surgery. Perioperative handling of antiplatelet drugs was evaluated. This review summarizes literature on the perioperative handling of antiplatelet drugs and analyzes the pharmacokinetic and pharmacodynamic characteristics of newer agents.
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