Key result
Clopidogrel 75 mg once daily resulted in significantly fewer safety events compared to ticlopidine 200 mg once daily (7.0% vs 15.1%, p<0.001) in Japanese patients with noncardioembolic stroke.
RCT
Double-blind
Absolute Event Rate: 7% vs 15.1%
p-value: p=<0.001
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Supports preferring clopidogrel over ticlopidine to reduce adverse events in Japanese noncardioembolic stroke patients; confirms RCT safety data in this population.
Fukuuchi et al. (2007) conducted an RCT in Noncardioembolic cerebral infarction. Clopidogrel vs. Ticlopidine 200 mg once daily was evaluated on Safety events (p=<0.001). Clopidogrel 75 mg once daily resulted in significantly fewer safety events compared to ticlopidine 200 mg once daily (7.0% vs 15.1%, p<0.001) in Japanese patients with noncardioembolic stroke.
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