Key result
A 60-year-old male developed a fatal pericardial-oesophageal fistula and purulent cardiac tamponade two weeks after undergoing radiofrequency ablation for atrial fibrillation.
Why the study?
Pericardial/atrial oesophageal fistula is a feared, infrequent, and rapidly fatal complication of AF ablation requiring urgent surgical treatment.
Case Report (n=1)
Pericardial-oesophageal fistula is a rare, rapidly fatal complication of AF ablation that can present atypically (e.g., mimicking STEMI) and requires high clinical suspicion for early detection.
Requires vigilance for delayed fistula post-AF ablation; extends limited case evidence without altering practice.
Background: Pericardial/atrial oesophageal fistula (PEF/AEF) is the most feared complication of cardiac atrial fibrillation (AF) ablation. Without urgent surgical treatment, most cases of this infrequent complication rapidly prove fatal. Case report: We present an uncommon case of a 60-year-old male who had undergone an AF ablation 2 weeks prior and presented with chest pain. Following diagnosis and treatment of ST-elevation myocardial infarction (STEMI), a small pericardial effusion was noticed on computed tomography (CT) scan. Despite an initially reassuring hospital course, rapid decompensation and expansion of his purulent pericardial effusion led to his death within 24 hours of presentation. A post-mortem review of his CT imaging revealed an inconspicuous PEF. Conclusions: It is essential to maintain a high suspicion of PEF/AEF in patients presenting after AF ablation with suggestive symptoms, such as fever, chest pain/odynophagia, and neurological deficits. CT chest is the most common diagnostic modality and surgical correction is the treatment of choice.
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Mansoor et al. (2025) conducted a case report in Pericardial-oesophageal fistula with cardiac tamponade (n=1). Radiofrequency ablation for atrial fibrillation was evaluated. A 60-year-old male developed a fatal pericardial-oesophageal fistula and purulent cardiac tamponade two weeks after undergoing radiofrequency ablation for atrial fibrillation.
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