The biochemical importance of the tetronic acid structure has been discussed in the preceding paper (3).This paper reports experiments designed to study the biosynthesis of penicillic acid (I), a member of the tetronic acid series known since 1913.This study is particularly interesting in view of the presence, in penicillic acid, of an isopropylidene side chain, a group which occurs only infrequently in natural products.
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Bentley et al. (1962) studied this question.
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