Why the study?
Do acute changes in plasma volume affect the stimulus-response relations of high- and low-pressure baroreflexes in men?
Population
8 men (27-44 yr old)
Comparison
Acute changes in plasma volume vs Normovolemic condition
Design
Other
Authors
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Hypovolemia augments cardiopulmonary baroreflex gain and vasoconstrictor demand; hypothesis-generating for orthostatic responses, clinical translation open.
Do acute changes in plasma volume affect the stimulus-response relations of high- and low-pressure baroreflexes in men?
Progressive hypovolemia increases the demand for vasoconstriction for equal reductions in venous pressure, which may compromise the capacity to provide adequate peripheral resistance during severe orthostatic stress.
Thompson et al. (1990) studied this question.
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