Why the study?
Does current use of non-aspirin NSAIDs reduce the risk of first-time acute myocardial infarction in patients without preexisting cardiovascular or metabolic diseases?
Does current use of non-aspirin NSAIDs reduce the risk of first-time acute myocardial infarction in patients without preexisting cardiovascular or metabolic diseases?
Current exposure to NSAIDs in patients without prior cardiovascular or metabolic disease does not decrease the risk of first-time acute myocardial infarction, suggesting no clinically relevant cardioprotective effect.
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No cardioprotective effect seen with NSAIDs in low-risk patients; leaves open any AMI association pending higher-level evidence.
Schlienger et al. (2002) studied this question.
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