Population
Canine skeletal muscle preparations in situ
Design
Preclinical
Authors
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Pharmacological reserve exceeds contraction-induced flow in canine muscle; leaves open translation to human perfusion or therapy.
In canine skeletal muscle, blood flow during contractions is determined by metabolic rate, but a pharmacological reserve exists allowing higher flows with vasodilators like adenosine.
J. K. Barclay (1988) studied this question.
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