Key result
Patients with established coronary artery disease had significantly lower total longitudinal displacement of the common carotid artery compared to healthy volunteers (0.112 vs 0.543, P<0.0001).
Why the study?
Can velocity vector imaging (VVI) assess longitudinal wall motion of the common carotid artery and differentiate between healthy volunteers and patients with coronary artery disease?
Population
32 individuals, comprising 16 healthy volunteers and 16 patients with established coronary artery disease.
Comparison
Velocity vector imaging analysis of standard… vs Healthy volunteers compared to CAD patients.
Design
Cross-sectional
Authors
Loading...
Supports VVI for carotid longitudinal motion assessment; hypothesis-generating for CAD biomarker, needs prospective validation.
Cross-Sectional (n=32)
Can velocity vector imaging (VVI) assess longitudinal wall motion of the common carotid artery and differentiate between healthy volunteers and patients with coronary artery disease?
Absolute Event Rate: 0.112% vs 0.543%
p-value: p=<0.0001
Velocity vector imaging is a feasible technique for assessing longitudinal common carotid artery wall motion, demonstrating significantly reduced motion in patients with coronary artery disease, suggesting its potential as a novel vascular biomarker.
Svedlund et al. (2010) conducted a cross-sectional in Coronary artery disease (n=32). Coronary artery disease (CAD) vs. Healthy volunteers was evaluated on Total longitudinal displacement (tLoD) of the common carotid artery (p=<0.0001). Patients with established coronary artery disease had significantly lower total longitudinal displacement of the common carotid artery compared to healthy volunteers (0.112 vs 0.543, P<0.0001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: