Key result
The HEART score outperformed TIMI and GRACE scores in predicting 30-day major adverse cardiovascular events (C statistic 0.937 vs 0.844 and 0.797, respectively; p<0.0001).
Why the study?
Data were lacking on whether the HEART score outperforms TIMI and GRACE scores for predicting MACE, particularly in the era of high-sensitivity troponin assays and in an exclusively Latin-American population.
Does the HEART score outperform TIMI and GRACE scores in predicting 30-day MACE in patients presenting with chest pain?
Cohort (n=519)
Does the HEART score outperform TIMI and GRACE scores in predicting 30-day MACE in patients presenting with chest pain?
Effect estimate: C statistic 0.937
p-value: p=< 0.0001
The HEART score outperforms TIMI and GRACE scores for predicting 30-day MACE in chest pain patients evaluated with high-sensitivity troponin, offering precise identification of low-risk patients.
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May support HEART score preference for 30-day MACE stratification; leaves open prospective validation before practice change.
Torralba et al. (2020) conducted a cohort in Chest pain (n=519). HEART score vs. TIMI and GRACE scores was evaluated on Occurrence of MACE within 30 days (C statistic 0.937, p=< 0.0001). The HEART score outperformed TIMI and GRACE scores in predicting 30-day major adverse cardiovascular events (C statistic 0.937 vs 0.844 and 0.797, respectively; p<0.0001).
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