Phytoestrogen Intake Correlate with Blood Pressure in Minangkabau Premenopausal People

Prevalence of hypertension increases in the premenopausal phase due to changes in estrogen levels. Phytoestrogens is known as estrogens like estrogen derived from plants. This study aims to elucidate the correlation of phytoestrogen intake with blood pressure in Minangkabau premenopausal people. A cross-sectional study was conducted in Minangkabau premenopausal people, aged 40–55 years old at Padang City in West Sumatera, Indonesia. Phytoestrogen intake examined to 76 subject by using food frequenty questionnaire (FFQ) that contain 200 kinds of food. Data were analyzed by using correlation test with significant levels p < 0.05. Blood pressure was measured in a sitting position after the subject rests for 10 minutes. Serum estradiol was measured by ELISA tecnique using E2 (estradiol) ELISA KIT from Elabscience. This study show that mean systolic blood pressure (SBP) is 119.74±16.1 mmHg and diastolic blood pressure (DBP) is 76.32±11.1 mmHg. Mean of phytoestrogens intake is 32.66±26.63 mg. The correlation test showed that there was a significant correlation between phytoestrogen intake with SBP (r=−0.255; p=0.26) and DBP (r=−0.246; p=0.032). Whereas serum estradiol levels did not show significant correlation with both SBP and DBP (r=−0.177; p=0.125 and r=−0.204: p=0.077) respectively. Phytoestrogens intake has significant correlation with blood pressure in Minangkabau premenopausal people.