Key result
Surgical resection followed by postoperative radiation therapy resulted in no recurrence of epithelioid angiosarcoma of the kidney at six months after surgery.
Case Report (n=1)
Epithelioid angiosarcoma of the kidney is a rare malignancy that can be diagnosed using immunohistochemical markers such as CD31, CK7, E-cadherin, and vimentin.
May support resection plus radiation for rare renal angiosarcoma; single case leaves optimal therapy unestablished.
Epithelioid angiosarcoma (EAS) is a rare disease which presents a great diagnostic challenge. The present study reports a case of EAS in the kidney in a 75-year-old male who presented with gross hematuria. An abdominal computed tomography scan revealed space-occupying lesions of the right kidney and renal cell carcinoma was suspected. Histological examination of the resected specimens showed pleomorphic epithelioid cells with vesicular nuclei, prominent nucleoli and eosinophilic cytoplasm that lined irregular vascular spaces. Immunohistochemical staining revealed that the tumor cells were positive for AE1/AE3, cytokeratin (CK) 7, vimentin, cluster of differentiation (CD) 31 and E-cadherin, but showed no staining for CD10, CD34, factor VIII, CK20, carcinoembryonic antigen or desmin. Based on the histopathological and immunohistochemical findings, the patient was diagnosed with epithelioid angiosarcoma. Postoperative radiation therapy was administered and no recurrence was observed six months after surgery.
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Liu et al. (2014) conducted a case report in Epithelioid angiosarcoma of the kidney (n=1). Surgical resection and postoperative radiation therapy was evaluated on Recurrence. Surgical resection followed by postoperative radiation therapy resulted in no recurrence of epithelioid angiosarcoma of the kidney at six months after surgery.
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