Key result
Among newly diagnosed adults with type 1 diabetes, the overall prevalence of diabetic ketoacidosis was 38%, and age 18-25 years significantly increased the odds of DKA compared to age 25-35 years (AOR 3).
Why the study?
Little is known about precipitating factors and clinical-laboratory features of DKA among Ethiopian patients, and information is scant to promote better health services to prevent mortality.
Population
Newly diagnosed patients with type one diabetes mellitus at Dilla University Referral Hospital
Design
Cross-sectional study
Authors
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Alerts clinicians to high DKA risk at T1D diagnosis in young adults; hypothesis-generating for targeted prevention studies.
Cross-Sectional (n=421)
No
Odds Ratio: 3 (95% CI 2–10)
Absolute Event Rate: 54% vs 4.4%
p-value: p=0.005
The prevalence of DKA among newly diagnosed type 1 diabetes patients in South Ethiopia is high (38%), strongly associated with young age, family history of DM, and preceding infection.
Alem et al. (2020) conducted a cross-sectional in Newly diagnosed Type 1 Diabetes Mellitus (n=421). Age 18-25 years vs. Age 25-35 years was evaluated on Diabetic Ketoacidosis (DKA) at primary diagnosis (AOR 3, 95% CI 2-10, p=0.005). Among newly diagnosed adults with type 1 diabetes, the overall prevalence of diabetic ketoacidosis was 38%, and age 18-25 years significantly increased the odds of DKA compared to age 25-35 years (AOR 3).
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