Periurethral Anaerobic Microflora in Girls Highly Susceptible to Urinary Tract Infections

No AccessJournal of Urology1 May 1981Periurethral Anaerobic Microflora in Girls Highly Susceptible to Urinary Tract Infections Ingela Bollgren, Carl-Erik Nord, Lena Pettersson, and Jan Winberg Ingela BollgrenIngela Bollgren More articles by this author , Carl-Erik NordCarl-Erik Nord More articles by this author , Lena PetterssonLena Pettersson More articles by this author , and Jan WinbergJan Winberg More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)55178-2AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail This investigation characterizes the anaerobic and aerobic periurethral microfloras in 11 premenarchal girls prone to urinary tract infections. The findings were compared to data from a previous study on the indigenous periurethral floras in 18 healthy girls. Periurethral colonization with Enterobacteriaceae often precedes urinary infections. The present study is part of an investigation of this periurethral abnormality in girls susceptible to urinary infections. A quantitative sampling technique was used. Two periurethral samples for anaerobic cultivation were obtained at I-week intervals from each girl. The mean value of the findings in each of the 2 samples was used in the statistical comparison between the girls prone to infection and the healthy controls. On the average 6. 7 anaerobic and 2.8 aerobic different types of organisms per sample were isolated. The mean total viable counts per cm.2 of periurethral area was 3.3 times 105, with strictly anaerobic bacteria constituting 90 per cent (median value) of the total bacterial counts. The girls prone to urinary infections were found to have an increased colonization with anaerobic gramnegative rods, primarily bacteroides, quantitatively (p less than 0.01) and with respect to average numbers of different types of anaerobic gram-negative rods per specimen (p less than 0.01). This increased colonization with anaerobic gram-negative rods showed no correlation with the appearance of Enterobacteriaceae periurethrally or with reinfection. Hypothetically, the findings may be related to the increased bacterial adhesive ability ofperiurethral epithelial cells in individuals prone to urinary infections. The possible role of preceding treatment with chemotherapy in the causation of the disturbed microflora deserves further attention. © 1981 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 125Issue 5May 1981Page: 715-720 Advertisement Copyright & Permissions© 1981 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Ingela Bollgren More articles by this author Carl-Erik Nord More articles by this author Lena Pettersson More articles by this author Jan Winberg More articles by this author Expand All Advertisement PDF DownloadLoading ...