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September 29, 2021Biomedical Science and EngineeringOpen Access

Towards reliable in vitro models – New bi-compartmental platforms for replicating tissue barriers

L. P. Coppadoro Elia Pederzani Chiara Foglieni Maria Lombardi Gianfranco Beniamino Fiore Monica Soncini

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Abstract

In vitro cell cultures represent a widespread methodology for pathophysiology studies with a high benefit/cost ratio. We have developed and are validating TToP, a novel, versatile, and scalable culture system allowing compartmentalized cell/tissue cultures with the aim of mimicking the human pathophysiological microenvironment of tissue barriers.

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Coppadoro et al. (2021) studied this question.

synapsesocial.com/papers/6a71c049c2d7c30908271cfc https://doi.org/10.4081/bse.2021.166

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