Key result
Two cases of ticagrelor non-responsiveness during cerebrovascular procedures demonstrate that inadequate platelet inhibition can occur, prompting a proposed management algorithm.
Why the study?
Although platelet inhibition testing is often forgone with ticagrelor, patients may rarely experience ticagrelor non-responsiveness during cervical and intracranial stenting.
Population
Two patients with ticagrelor non-responsiveness from two high-volume cerebrovascular centers
Design
Case series
Authors
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Ticagrelor non-responsiveness may occur in cerebrovascular procedures, warranting vigilance; leaves open validation of proposed platelet testing algorithms.
Case Report (n=2)
Yes
Highlights the rare occurrence of ticagrelor non-responsiveness in neurointerventional procedures and provides a management algorithm.
Laurent et al. (2021) conducted a case report in Ticagrelor non-responsiveness (n=2). Ticagrelor was evaluated. Two cases of ticagrelor non-responsiveness during cerebrovascular procedures demonstrate that inadequate platelet inhibition can occur, prompting a proposed management algorithm.
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