Key result
High frequency and appropriately increased differential pressure of triangle wave pulsating flow improved the effect of dredging blood embolism in a lattice Boltzmann method simulation.
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Computational modeling suggests that high-frequency triangle wave pulsating flow with increased differential pressure may be effective in dredging blood embolisms.
As one of the major causes of cardiovascular diseases, the formation mechanism and the external factors of blood embolism are always the concerned problems of medical field, biological and physical field. Owing to thrombotic formation and structure being complicated, the difficulty in curing thrombosis greatly increases. Pulsation flows have a positive effect on dredging blood embolism. Owing to the blood viscosity and the inertia of red blood cells, waveform, amplitude and frequency of pulsating flow will influence the effect of dredging blood embolism. The research in this paper is mainly based on the lattice Boltzmann method. In conical pipe with embolism, in order to explore the influences of triangle wave pulsating flow waveform, the effects of differential pressure and frequency on vascular thrombus are studied by calculating the effect of dredging blood embolism. Calculation shows that the effect of dredging blood embolism is not obvious under the condition of low frequency and low differential pressure. On the contrary, the effect is good under the condition of high frequency. Appropriately increasing the differential pressure can also improve the frequency of the triangular wave of the bolt.
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Yan-Hua et al. (2016) studied Blood embolism / vascular thrombus. Triangle wave pulsating flow (high frequency and differential pressure) vs. Low frequency and low differential pressure was evaluated on Effect of dredging blood embolism. High frequency and appropriately increased differential pressure of triangle wave pulsating flow improved the effect of dredging blood embolism in a lattice Boltzmann method simulation.
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