Pancreatic Tumor Associated with Flushing and Diarrhea

THE association of noninsulin-producing islet-cell adenomas of the pancreas, profuse diarrhea and hypokalemia with hypokalemic nephropathy has previously been reported. The following patient was successfully treated by removal of a large adenoma.Case ReportC.Q., a 49-year-old baker, first noted the onset of his illness in December, 1943, with the sudden appearance of pronounced flushing of the face and upper trunk and a generalized throbbing headache lasting 15 to 30 minutes and followed by a copious outpouring of watery brown stool. These episodes occurred 5 to 10 times daily. The symptoms subsided in 3 days, but bowel activity remained abnormal. . . .