Plasma and whole blood based scaffolds were used for cartilage tissue engineering. Chondrocytes were isolated, embedded into these structures, and cultivated for two weeks. To evaluate the neo-synthesized extracellular matrix quantitatively, the constructs were examined by classical techniques and NMR spectroscopy. Significant expression of characteristic extracellular matrix was found suggesting that these materials are well-suited grafts for artificial tissue.
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Haberhauer et al. (2008) studied this question.
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