Key result
Endothelial dysfunction impacts cardiovascular disease through its role in anti-coagulation, inflammation, and vaso-regulation, with its mechanisms offering potential targets for novel therapies.
Why the study?
To review the impact of endothelial dysfunction on cardiovascular disease and assess its clinical relevance, noting that continued investigation of its mechanisms may lead to novel therapies.
This review highlights the role of endothelial dysfunction in cardiovascular disease and its potential as a target for novel therapies.
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Endothelial-targeted therapies should not yet change practice; leaves open validation in prospective cardiovascular trials.
Little et al. (2021) conducted a review in Cardiovascular disease. Endothelial dysfunction was evaluated. Endothelial dysfunction impacts cardiovascular disease through its role in anti-coagulation, inflammation, and vaso-regulation, with its mechanisms offering potential targets for novel therapies.
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