Why the study?
Complications such as screw cut-out and rotational instability persist with standard PFN in unstable intertrochanteric fractures, prompting the development of PFNA2 with a helical blade to enhance fixation and stability in osteoporotic bone.
Does PFNA2 improve clinical and radiological outcomes compared to standard PFN in patients with unstable intertrochanteric fractures?
Population
50 patients with unstable intertrochanteric fractures (AO 31.A2 and 31.A3)
Comparison
PFN vs PFNA2
Design
Prospective comparative study
Follow-up
Six months
Key result
PFNA2 significantly improved 6-month Harris Hip Scores (88.57 vs 76.23, p=0.014) and accelerated mean bone union time (14.69 vs 18.47 weeks) compared to standard PFN in intertrochanteric fractures.
Authors
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Supports PFNA2 in osteoporotic intertrochanteric fractures; leaves open need for RCTs versus PFN.
RCT (n=50)
Open-label
Randomized
No
Does PFNA2 improve clinical and radiological outcomes compared to standard PFN in patients with unstable intertrochanteric fractures?
Absolute Event Rate: 88.57% vs 76.23%
p-value: p=0.014
PFNA2 demonstrated significantly faster bone union and better functional outcomes compared to standard PFN for unstable intertrochanteric fractures.
Kumar et al. (2024) conducted an RCT in Unstable intertrochanteric fractures (n=50). Proximal Femoral Nail Antirotation for Asia (PFNA2) vs. Standard Proximal Femoral Nail (PFN) was evaluated on Harris Hip Score at 6 months (p=0.014). PFNA2 significantly improved 6-month Harris Hip Scores (88.57 vs 76.23, p=0.014) and accelerated mean bone union time (14.69 vs 18.47 weeks) compared to standard PFN in intertrochanteric fractures.