Case report reveals fatal bronchiolitis obliterans complicating Stevens-Johnson syndrome in a pediatric patient, highlighting critical safety concerns regarding nimesulide use.
Nimesulide is a frequently used non-steroidal anti-inflammatory drug with analgesic and antipyretic effects in children. In view of fatal adverse drug reactions, however, its safety has been questioned. A 5-year-old boy developed Stevens-Johnson syndrome following use of nimesulide which was later complicated by rapidly progressive fatal bronchiolitis obliterans.
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Dogra et al. (2011) studied this question.
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