Key result
Age under 40 years was associated with a significantly higher risk of smoking relapse compared to age over 60 years (HR 19.142), alongside cohabitation and frequent depression.
Why the study?
Given the harm of smoking and relapse following cessation despite global tobacco control efforts, this study aimed to establish a competing risk model to determine potential risk factors for smoking relapse.
Cohort (n=1,019)
Hazard Ratio: 19.142 (95% CI 10.641–34.434)
p-value: p=<0.01
In a Chinese cohort of ex-smokers, younger age, cohabitation, and frequent depression were identified as strong predictors of smoking relapse, highlighting target populations for intensive cessation support.
Younger age and depression were associated with higher relapse risk; leaves open targeted prevention strategies for prospective validation.
Background Tobacco use is still highly prevalent globally in spite of the tobacco control efforts made by the governments. In view of the harm of smoking and relapse after smoking cessation, the purpose of this study is to establish a competitive risk model to determine potential risk factors for smoking relapse. Methods The population-based cohort of ex-smokers over the age of 18 years was obtained from the China Family Panel Studies (CFPS) database from 2010 to 2018. Competing risk models were conducted to identify the risk factors for relapse. Results A total of 1,019 subjects were included in this study, of which 311 (30.52%) subjects relapsed during the follow-up period. A multivariate analysis indicated that age < 40 years [hazard ratio (HR) 19.142; 95% CI: 10.641–34.434, p < 0.01], cohabitation ( HR : 1.422; 95% CI : 1.081–1.87, p = 0.01), and often depression [ HR 1.422; 95% CI , (1.081–1.87), p = 0.01] were associated with a great risk of relapse while the age of quitting smoking < 60 years ( HR : 0. 436; 95% CI : 0.229–0.831, p < 0.01) and joining the Chinese Communist Party (CCP) ( HR 0.611; 95% CI : 0.397–0.939, p = 0.03) were reduced risk factors for relapse. Conclusions Approximately 3 in 10 ex-smokers were observed to relapse. There are various risk factors for relapse as well. In the face of such a serious situation, it is urgent to take action to control smoking.
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Hu et al. (2022) conducted a cohort in Smoking cessation (n=1,019). Age < 40 years vs. Age > 60 years was evaluated on Smoking relapse (HR 19.142, 95% CI 10.641-34.434, p=<0.01). Age under 40 years was associated with a significantly higher risk of smoking relapse compared to age over 60 years (HR 19.142), alongside cohabitation and frequent depression.
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