Key result
Pretreatment with prophylactic antiarrhythmic drugs significantly improved the immediate success rate of electrical cardioversion for atrial fibrillation compared to no antiarrhythmic drugs (75.6% vs. 62.7%).
Why the study?
Does electrical cardioversion effectively restore and maintain sinus rhythm in patients with atrial fibrillation in a managed care setting?
Cohort (n=370)
No
Does electrical cardioversion effectively restore and maintain sinus rhythm in patients with atrial fibrillation in a managed care setting?
Absolute Event Rate: 75.6% vs 62.7%
p-value: p=0.027
In a managed care setting, electrical cardioversion for atrial fibrillation has an initial success rate of 66%, with shorter AF duration and prophylactic antiarrhythmics improving initial success, though younger patients with paroxysmal AF and alcohol use have higher recurrence rates.
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May support prophylactic antiarrhythmics before AF cardioversion; hypothesis-generating and requires randomized confirmation before practice change.
Kuppahally et al. (2009) conducted a cohort in Atrial fibrillation (n=370). Prophylactic antiarrhythmic drugs vs. No antiarrhythmic drugs was evaluated on Immediate success of electrical cardioversion (p=0.027). Pretreatment with prophylactic antiarrhythmic drugs significantly improved the immediate success rate of electrical cardioversion for atrial fibrillation compared to no antiarrhythmic drugs (75.6% vs. 62.7%).
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