Key result
Obesity was associated with significantly increased short-term blood pressure variability in patients with hypertension, with 24-hour SDw SBP reaching 14.1 in obese patients compared to 11.4 in normal-weight patients (p=0.001).
Why the study?
Short-term blood pressure variability is an independent risk factor in hypertension, and overweight and obesity are considered potential influencing factors.
Does overweight and obesity increase short-term blood pressure variability in patients with hypertension?
Cross-Sectional (n=111)
Open-label
Does overweight and obesity increase short-term blood pressure variability in patients with hypertension?
Absolute Event Rate: 14.1% vs 11.4%
p-value: p=0.001
Suggests BP variability monitoring in obese hypertensives; hypothesis-generating and should not change practice.
Annotation. Short-term blood pressure (BP) variability (VAR) is an independent risk factor in patients with hypertension. Overweight and obesity are considered to be some of the factors influencing BP VAR. The aim of the study was to study the effect of overweight and obesity on the parameters of short-term BP VAR in patients with hypertension. The study involved 111 patients with hypertension, who were divided into three groups depending on the body mass index (BMI) - normal weight, overweight and obesity. All patients underwent 24-hour blood pressure monitoring (ABPM), the results of which were used to assess short-term BP VAR. Statistical analysis of the results was carried out using Microsoft Excel spreadsheets and the STATISTICA 5.5 program. Most of the studied short-term BP VAR parameters were the highest in the group of obese patients. It was established that there is a positive relationship between BMI and short-term BP VAR parameters. Overweight and obesity must be considered as contributing factors to increased BP variability.
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Kanishcheva et al. (2020) conducted a cross-sectional in Hypertension (n=111). Obesity (BMI > 30.0 kg/m2) vs. Normal weight (BMI 18.5-24.9 kg/m2) was evaluated on 24-hour weighted standard deviation of systolic blood pressure (SDw SBP) (p=0.001). Obesity was associated with significantly increased short-term blood pressure variability in patients with hypertension, with 24-hour SDw SBP reaching 14.1 in obese patients compared to 11.4 in normal-weight patients (p=0.001).
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