Key result
The modified triglyceride-glucose-waist-height ratio (TyG-WHtR) was strongly associated with arterial stiffness in overweight or obese adults, with the highest quartile showing a significantly increased risk (OR 3.071).
Why the study?
The study aimed to investigate the correlation between the TyG index and its modified indices with arterial stiffness in overweight or obese individuals, exploring novel modified TyG indices.
Do elevated triglyceride-glucose (TyG) indices correlate with increased arterial stiffness in overweight or obese adults?
Cross-Sectional (n=1,143)
No
Do elevated triglyceride-glucose (TyG) indices correlate with increased arterial stiffness in overweight or obese adults?
Odds Ratio: 3.071 (95% CI 1.496–6.303)
p-value: p=0.002
Modified triglyceride-glucose indices, particularly TyG-WHtR and TyG-1h, are effective and accessible surrogate markers for identifying arterial stiffness in overweight or obese adults.
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Supports TyG indices for arterial stiffness screening in obesity; hypothesis-generating and needs prospective validation before clinical adoption.
Tang et al. (2024) conducted a cross-sectional in Overweight or obesity (n=1,143). TyG-WHtR (highest quartile) vs. TyG-WHtR (lowest quartile) was evaluated on Arterial stiffness (baPWV ≥ 1400 cm/s) (OR 3.071, 95% CI 1.496-6.303, p=0.002). The modified triglyceride-glucose-waist-height ratio (TyG-WHtR) was strongly associated with arterial stiffness in overweight or obese adults, with the highest quartile showing a significantly increased risk (OR 3.071).
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