Key result
Readmission to a non-index hospital within 90 days of total joint replacement was associated with significantly higher 90-day mortality compared to index hospital readmission (aOR 1.69).
Why the study?
It is unclear whether mortality outcomes differ for patients undergoing THA or TKA who are readmitted to the index hospital where surgery was performed versus another hospital.
Does readmission to a non-index hospital increase mortality in patients readmitted within 90 days following total joint replacement?
Cohort (n=394,248)
Yes
Does readmission to a non-index hospital increase mortality in patients readmitted within 90 days following total joint replacement?
Odds Ratio: 1.69 (95% CI 1.39–2.05)
Absolute Event Rate: 1.8% vs 0.9%
Readmission to a non-index hospital following total joint replacement is associated with significantly higher 90-day and one-year mortality compared to readmission to the index hospital.
Non-index readmission after THA/TKA was associated with higher mortality; leaves open whether targeted transfer protocols could improve outcomes in observational data.
Aims: It is unclear whether mortality outcomes differ for patients undergoing total hip arthroplasty (THA) or total knee arthroplasty (TKA) surgery who are readmitted to the index hospital where their surgery was performed, or to another hospital. Methods: We analyzed linked hospital and death records for residents of New South Wales, Australia, aged ≥ 18 years who had an emergency readmission within 90 days following THA or TKA surgery between 2003 and 2022. Multivariable modelling was used to identify factors associated with non-index readmission and to evaluate associations of readmission destination (non-index vs index) with 90-day and one-year mortality. Results: Of 394,248 joint arthroplasty patients (THA = 149,456; TKA = 244,792), 9.5% (n = 37,431) were readmitted within 90 days, and 53.7% of these were admitted to a non-index hospital. Non-index readmission was more prevalent among patients who underwent surgery in private hospitals (60%). Patients who were readmitted for non-orthopaedic conditions (62.8%), were more likely to return to a non-index hospital compared to those readmitted for orthopaedic complications (39.5%). Factors associated with non-index readmission included older age, higher socioeconomic status, private health insurance, and residence in a rural or remote area. Non-index readmission was significantly associated with 90-day (adjusted odds ratio (aOR) 1.69; 95% confidence interval (CI) 1.39 to 2.05) and one-year mortality (aOR 1.31; 95% CI 1.16 to 1.47). Associations between non-index readmission and mortality were similar for patients readmitted with orthopaedic and non-orthopaedic complications (90-day mortality aOR 1.61; 95% CI 0.98 to 2.64, and aOR 1.67; 95% CI 1.35 to 2.06, respectively). Conclusion: Non-index readmission was associated with increased mortality, irrespective of whether the readmission was for orthopaedic complications or other conditions.
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Shawon et al. (2024) conducted a cohort in Total hip or knee arthroplasty (n=394,248). Non-index hospital readmission vs. Index hospital readmission was evaluated on 90-day mortality (aOR 1.69, 95% CI 1.39 to 2.05). Readmission to a non-index hospital within 90 days of total joint replacement was associated with significantly higher 90-day mortality compared to index hospital readmission (aOR 1.69).
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