What question did this study set out to answer?

To evaluate the performance characteristics and diagnostic accuracy of the Glasgow Meningococcal Septicemia Prognostic Score in predicting mortality.

January 1, 1991Critical Care Medicine

Validation of the Glasgow Meningococcal Septicemia Prognostic Score

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Authors

ATAlistair ThomsonNational Health Service JSJohn SillsGoogle (United States)CHCarole HartHeliophysics

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Implication

Retrospective case-note study demonstrates high prognostic accuracy of the GMSPS in pediatric meningococcal septicemia, suggesting its utility for early intensive care triage.

Key Points

To evaluate the performance characteristics and diagnostic accuracy of the Glasgow Meningococcal Septicemia Prognostic Score in predicting mortality.
Retrospective case-note study conducted across two pediatric hospitals with a regional intensive care unit.
Included 123 children with proven meningococcal septicemia (some with concurrent meningitis) admitted between January 1, 1977, and December 31, 1986.
All 14 children who died scored ≥ 8 on admission (n = 8) or afterward (n = 6), compared to only 5 of 109 survivors scoring ≥ 8.
A GMSPS cutoff of ≥ 10 predicted mortality with 100% sensitivity, 98% specificity, and an 88% positive predictive value.
Cutoffs of GMSPS ≥ 8 or ≥ 9 both demonstrated 100% sensitivity, 95% specificity, and a 74% positive predictive value for death.

Cite This Study

Thomson et al. (1991) studied this question.

synapsesocial.com/papers/6a71d69b5671bbf00bc2f7d9 https://doi.org/10.1097/00003246-199101000-00010

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Implication

Retrospective case-note study demonstrates high prognostic accuracy of the GMSPS in pediatric meningococcal septicemia, suggesting its utility for early intensive care triage.

Validation of the Glasgow Meningococcal Septicemia Prognostic Score

Discussion

Member takes

Implication

Key Points

Cite This Study

Validation of the Glasgow Meningococcal Septicemia Prognostic Score

Discussion

Member takes

Implication

Key Points

Cite This Study

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