What question did this study set out to answer?

To evaluate the efficacy of SII, PIV, and mGPS in assessing severity and predicting outcomes in community-acquired pneumonia.

July 13, 2026BMC Pulmonary MedicineOpen Access

Incremental prognostic value of the systemic immune‑inflammation index, pan‑immune‑inflammation value, and modified glasgow prognostic score for severity assessment and outcome prediction in community‑acquired pneumonia

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To evaluate the efficacy of SII, PIV, and mGPS in assessing severity and predicting outcomes in community-acquired pneumonia.
Conducted a retrospective analysis of 1879 community-acquired pneumonia patients admitted from January 2021 to December 2023.
Categorized patients into mild and severe groups using the Pneumonia Severity Index (PSI).
Analyzed associations between SII, PIV, and mGPS with disease severity and prognosis using hierarchical logistic regression and ROC analysis.
SII and PIV levels are significantly higher in severe community-acquired pneumonia patients (P < 0.001).
mGPS is identified as the strongest independent predictor of severe CAP (OR = 18.342, P < 0.001).
Incorporating SII, PIV, and mGPS improved the AUC for predicting 28-day mortality from 0.672 to 0.712.

Authors

YLYunkui LiYangtze University YHY R HuFirst People’s Hospital of Jingmen LFLiming FanYunnan Agricultural University

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Implication

Retrospective analysis identifies immune-inflammation indices as valuable prognostic tools in community-acquired pneumonia, highlighting their utility in patient care.

Cite This Study

Li et al. (2026) studied this question.

synapsesocial.com/papers/6a548195475c38bf615a58b3 https://doi.org/10.1186/s12890-026-04422-9

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Implication

Retrospective analysis identifies immune-inflammation indices as valuable prognostic tools in community-acquired pneumonia, highlighting their utility in patient care.

Incremental prognostic value of the systemic immune‑inflammation index, pan‑immune‑inflammation value, and modified glasgow prognostic score for severity assessment and outcome prediction in community‑acquired pneumonia

Key Points

Discussion

Implication

Cite This Study

Incremental prognostic value of the systemic immune‑inflammation index, pan‑immune‑inflammation value, and modified glasgow prognostic score for severity assessment and outcome prediction in community‑acquired pneumonia

Key Points

Discussion

Implication

Cite This Study

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