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This research aims to explore the relationship between risk factors, disease severity, and inflammatory markers in community-acquired pneumonia.

Associations between patient risk factors, disease severity, and inflammatory markers in community-acquired pneumonia

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This research aims to explore the relationship between risk factors, disease severity, and inflammatory markers in community-acquired pneumonia.
Prospective study design conducted in a single center with 41 adults diagnosed with community-acquired pneumonia.
Participants' clinical data and inflammatory markers were collected upon admission and after 7 days of treatment.
Patients were categorized based on age, co-morbidities, and pneumonia severity index (PSI) classes.
Non-parametric tests and Spearman correlations were utilized for statistical analysis.
Patients over 65 years and those with co-morbidities exhibited significantly elevated IL-6 levels compared to younger, non-comorbid patients.
IL-6, IFNγ, and G-CSF levels were highest at admission and decreased by day 7, notably in lower PSI class patients.
Higher PSI classes correlated with increased levels of IL-6, IL-8, and IFNγ.
NLR and SII were significantly heightened in older patients and those in higher PSI classes.

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Prospective study finds that inflammatory markers correlate with disease severity in older adults, indicating better risk assessment.

Nutautienė et al. (2026) studied this question.

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