Why the study?
Coxsackievirus B3 commonly induces fulminant viral myocarditis, presenting a significant diagnostic dilemma because nonspecific flu-like symptoms can mimic other conditions like ACS or cardiomyopathy.
Population
One previously healthy 23-year-old female with fulminant CVB3 myocarditis
Design
Case report and literature review
Key result
A 23-year-old female with fulminant Coxsackievirus B3 myocarditis developed refractory cardiogenic shock, acute ischemic stroke, and multiorgan failure, resulting in death on hospital day 28.
Authors
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Supports early suspicion for CVB3 myocarditis in shock; leaves open prospective validation of diagnostic thresholds.
Case Report (n=1)
No
Fulminant Coxsackievirus B3 myocarditis can rapidly progress to refractory cardiogenic shock and severe thromboembolic complications despite maximal supportive therapy and prophylactic anticoagulation.
Jahoda et al. (2025) conducted a case report in Fulminant Coxsackievirus B3 myocarditis (n=1). Coxsackievirus B3 infection was evaluated. A 23-year-old female with fulminant Coxsackievirus B3 myocarditis developed refractory cardiogenic shock, acute ischemic stroke, and multiorgan failure, resulting in death on hospital day 28.