Why the study?
Does age influence arterial baroreflex inhibition of sympathetic nerve activity in healthy normotensive men?
Population
15 healthy normotensive men, comprising 8 young (age 25 +/- 1 yr) and 7 older (69 +/- 1 yr) subjects.
Comparison
Graded constant infusion of phenylephrine… vs Baseline control before infusion.
Design
Cross-sectional
Authors
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Preserved baroreflex MSNA inhibition with age; leaves open alternative mechanisms for elevated tonic sympathetic activity in healthy older men.
Does age influence arterial baroreflex inhibition of sympathetic nerve activity in healthy normotensive men?
Arterial baroreflex inhibition of muscle sympathetic nerve activity is preserved with age in healthy normotensive men, suggesting this mechanism does not contribute to the age-related rise in tonic MSNA.
Davy et al. (1998) studied this question.
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