Key result
Primary cardiac angiosarcoma is associated with a poor prognosis and mortality ranging from 64.7% to 100%, though surgical resection and adjuvant chemotherapy may improve survival.
Why the study?
Primary cardiac angiosarcomas carry a poor prognosis with short survival, and no consensus or guidelines exist regarding their clinical manifestations, management, and outcomes.
Population
Patients with primary cardiac angiosarcoma across six studies
Design
Systematic review of six studies (five case series, one cohort)
Authors
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PCA lacks evidence-based guidelines; leaves open need for prospective studies on optimal management.
Systematic Review (n=232)
Primary cardiac angiosarcoma is a rare, aggressive tumor with late presentation and high mortality, though surgical resection and adjuvant chemotherapy may offer some survival benefit.
Chambergo‐Michilot et al. (2023) conducted a systematic review in Primary cardiac angiosarcoma (n=232). Surgical resection and chemotherapy vs. Conservative management was evaluated on Mortality. Primary cardiac angiosarcoma is associated with a poor prognosis and mortality ranging from 64.7% to 100%, though surgical resection and adjuvant chemotherapy may improve survival.
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