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May 20, 2022Clinical Hemorheology and Microcirculation

Exercise with blood flow restriction improves muscle strength and mass while preserving the vascular and microvascular function and structure of older adults

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Key result

Low-intensity resistance training with mild blood flow restriction increased muscle mass more than high-intensity and low-intensity training without restriction (6% vs 2% and -1%, p<0.05).

Why the study?

The study evaluated changes in muscle mass, strength, vascular function, oxidative stress, and inflammatory biomarkers in older adults across different resistance training intensities with or without blood flow restriction.

Does low-intensity resistance training with blood flow restriction improve muscle strength, mass, and vascular function in older adults compared to resistance training without blood flow restriction?

Population

Thirty-two untrained individuals (72±7 y)

Comparison

RT-CON vs RT-BFR vs RT-HI

Design

Randomized trial

Follow-up

12-week

Authors

KLKarynne Grutter LopesPFPaulo FarinattiDBDaniel Bottino

Discussion

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Member takes

Overview

Low-intensity BFR RT may safely increase strength and mass in older adults; leaves open efficacy versus high-intensity training in larger trials.

Study Design

Type

RCT (n=32)

Randomization

randomized

Structured PICO

Does low-intensity resistance training with blood flow restriction improve muscle strength, mass, and vascular function in older adults compared to resistance training without blood flow restriction?

P
Population
32 untrained older adults (mean age 72 years) randomized to a 12-week resistance training program.
I
Intervention
12-week low-intensity resistance training (30% of 1 repetition maximum) with mild blood flow restriction (50% of arterial occlusion pressure)
C
Comparator
12-week low-intensity resistance training without blood flow restriction (30% of 1RM) and high-intensity resistance training without blood flow restriction (70% of 1RM)
O
Outcome
Changes in muscle mass, strength, vascular function, oxidative stress, and inflammatory biomarkerssurrogate

Main Result

Absolute Event Rate: 6% vs -1%

p-value: p=< 0.05

Low-intensity resistance training with mild blood flow restriction improves muscle strength and mass while preserving vascular function in older adults, offering an alternative for those intolerant to high loads.

Cite This Study

Lopes et al. (2022) conducted an RCT in untrained older adults (n=32). Low-intensity resistance training with mild blood flow restriction (RT-BFR) vs. Low-intensity without BFR (RT-CON) and high-intensity without BFR (RT-HI) was evaluated on Increase in muscle mass (p=< 0.05). Low-intensity resistance training with mild blood flow restriction increased muscle mass more than high-intensity and low-intensity training without restriction (6% vs 2% and -1%, p<0.05).

synapsesocial.com/papers/6a71e4a2ac440176ef2a6845https://doi.org/10.3233/ch-221395
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Also Consider

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