What question did this study set out to answer?

Investigate the long-term impact of early profound auditory sensory deprivation and cochlear implant stimulation on the maturation of the central auditory cortex.

January 1, 2001Audiology and Neurotology

Of Kittens and Kids: Altered Cortical Maturation following Profound Deafness and Cochlear Implant Use

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Authors

CPCurtis W. PontonMedical University of South Carolina JEJos J. EggermontUniversity of Calgary

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Overview

Comparative neurophysiological study reveals persistent auditory cortex immaturity in cochlear implant users, indicating incomplete cortical maturation despite long-term stimulation.

Key Points

Investigate the long-term impact of early profound auditory sensory deprivation and cochlear implant stimulation on the maturation of the central auditory cortex.
Analyzed longitudinal and cross-sectional scalp-recorded cortical auditory evoked potentials in normal-hearing peers and profoundly deaf children using cochlear implants into their late teens.
Compared human evoked potentials with cortical surface local field potentials recorded in deaf white kittens undergoing electrical stimulation via cochlear implants.
Cochlear implant users showed persistent cortical alterations through late adolescence, including prolonged P1 peak latency, markedly larger P1 amplitude, and an absence of the normal N1b peak.
Age-related morphological alterations in the P1 peak ceased around 12 years of age in implanted users without attaining typical adult morphology.
Implanted deaf white kittens exhibited comparable deficits in cortical activation, linking abnormal waveform morphology to persistent axonal immaturity within superficial cortical layers.

Cite This Study

Ponton et al. (2001) studied this question.

synapsesocial.com/papers/6a71e64fa7fbea1e44088894 https://doi.org/10.1159/000046846

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January 1, 2001Audiology and Neurotology

Of Kittens and Kids: Altered Cortical Maturation following Profound Deafness and Cochlear Implant Use

View Full Paper

Ask AI

Bookmark

Authors

CPCurtis W. PontonMedical University of South Carolina JEJos J. EggermontUniversity of Calgary

Discussion

Member takes

Overview

Comparative neurophysiological study reveals persistent auditory cortex immaturity in cochlear implant users, indicating incomplete cortical maturation despite long-term stimulation.

Key Points

Investigate the long-term impact of early profound auditory sensory deprivation and cochlear implant stimulation on the maturation of the central auditory cortex.
Analyzed longitudinal and cross-sectional scalp-recorded cortical auditory evoked potentials in normal-hearing peers and profoundly deaf children using cochlear implants into their late teens.
Compared human evoked potentials with cortical surface local field potentials recorded in deaf white kittens undergoing electrical stimulation via cochlear implants.
Cochlear implant users showed persistent cortical alterations through late adolescence, including prolonged P1 peak latency, markedly larger P1 amplitude, and an absence of the normal N1b peak.
Age-related morphological alterations in the P1 peak ceased around 12 years of age in implanted users without attaining typical adult morphology.
Implanted deaf white kittens exhibited comparable deficits in cortical activation, linking abnormal waveform morphology to persistent axonal immaturity within superficial cortical layers.

Cite This Study

Ponton et al. (2001) studied this question.

synapsesocial.com/papers/6a71e64fa7fbea1e44088894 https://doi.org/10.1159/000046846

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