Circulation of enteroviruses and persistence of meningitis cases in the winter of 1999–2000

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Structured PICO

Population

115 patients (86 children, 29 adults) admitted for suspected meningitis from October 1, 1998 to April 30, 2000.

Intervention

In-house reverse transcription-polymerase chain reaction (RT-PCR) in cerebrospinal fluid (CSF)

Outcome

Incidence of enterovirus meningitis and seasonal variation

Enterovirus meningitis can persist through winter months, suggesting the clinical utility of year-round enterovirus RT-PCR testing.

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Enterovirus meningitis may occur in winter; supports year-round CSF RT-PCR consideration but leaves open need for prospective confirmation.

Chambon et al. (2001) studied this question.

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Enterovirus meningitis may occur in winter; supports year-round CSF RT-PCR consideration but leaves open need for prospective confirmation.